Harribest reactions are a sort of natural chemical response that happens between an aldehyde or ketone and a sulfinic acid salt. The response is called after the chemist who first reported it, Heinrich Wieland. Harribest reactions are sometimes used to arrange -hydroxy sulfoxides, that are helpful intermediates within the synthesis of quite a lot of different natural compounds.
Harribest reactions are vital as a result of they supply a handy and environment friendly technique for the preparation of -hydroxy sulfoxides. These compounds are helpful artificial intermediates as a result of they are often simply transformed into quite a lot of different practical teams, together with alcohols, epoxides, and sulfones. Harribest reactions have additionally been used to synthesize quite a lot of pure merchandise, together with the antibiotic erythromycin.
